一、中心简介
首都医学科学创新中心（简称创新中心）是北京市新成立的具有独立法人资格的新型研发机构。创新中心以推动医学科学发展、改善人类健康为目标，开展生物医学研究，致力于提升医学科学创新与成果转化能力，提高疾病诊断和治疗水平。我们将汇聚世界高水平科学家，与首都医学教育和科学研究优质资源紧密合作，打造多学科交叉融合的科研平台，综合自由探索、医学目标导向、有组织科研等途径，实践新型科研模式和体制机制，逐步推进医教研产的深度融合，培养适应医学科学创新发展的优秀人才。
二、实验室介绍
王立铭，首都医学科学创新中心资深研究员，遗传与分子医学研究所所长，博士生导师。
实验室长期关注机体代谢的神经生物学调控机理研究。在Nature、Nature Neuroscience、PNAS、e Life、Cell Research等知名期刊发表多篇研究论文。同时致力于大众科学传播和教育，出版专著《吃货的生物学修养》《上帝的手术刀》《生命是什么》《笑到最后》《给忙碌者的病毒科学》等科普书籍，发行量超30万册，先后获得国家图书馆“文津图书奖”、科技部全国优秀科普作品、“吴大猷科普著作奖”等奖励。
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三、实验室研究方向
包括人类在内，动物的生存和健康很大程度上依赖于对机体能量和必需营养物质水平的精确调节和维持，而中枢神经系统在这方面发挥了不可或缺的重要功能。通过实时的感知机体内部的能量和营养物质储备，以及环境中食物的分布，中枢神经系统可以通过精密的行为调节，保证动物机体的代谢平衡。而这一调控机制一旦被破坏，将可能引发包括进食障碍、肥胖症在内的一系列神经和代谢系统疾病。
实验室对神经系统与代谢系统相关联的生物学问题有广泛的兴趣。近期的研究工作将主要利用定量行为分析、活体钙成像、遗传筛选和分析、单细胞转录组和环路追踪等技术，在果蝇和小鼠模型中研究如下两个相互独立但互相关联的生物学问题：
l神经系统如何参与机体能量和重要营养物质代谢的调控
l动物各器官如何协同参与机体代谢的调控和代谢病的发生
四、岗位信息
岗位1：科研助理（若干）
01、岗位职责
1.协助团队或独立开展课题研究；
2.参与实验室日常管理，提供公共事务支持。
02、任职要求
1.细胞生物学、神经生物学相关专业硕士及以上学历，有相关实验技术经验者可放宽到本科；
2.抗压能力强，热爱科研，有志于继续从事科研工作；
3.品行端正，动手能力强，工作认真负责，具备良好的团队协作能力；
4.通过CET-6或同等英语水平，或有攻读研究生计划者优先。
03、研究方向
1.进行细胞方面的相关科研实验，日常的细胞事务管理、质粒的转染、稳转细胞系的构建、细胞染色、成像、KO文库和代谢物筛选等；
2.进行神经环路方面相关科研实验，脑立体定位注射、光纤记录、光/化学遗传学、双光子活体成像、组织透明化成像等；
3.进行果蝇神经环路方面相关科研实验，包括行为学检测、在体及离体钙成像、荧光脑片拍摄、光遗传学、果蝇库管理等。
岗位2：博士后（2名）
01、岗位职责
1.在导师及合作导师共同指导下参与实验室的课题研究；
2.协助处理实验室公共事务。
02、任职要求
1.获得或即将获得生物学/基础医学相关领域博士学位，毕业时间一般不超过三年；
2.以第一作者身份在领域内主流期刊发表过或即将发表研究论文；
3.具备独立开展科研工作能力，对科研有热情和严谨认真的态度，有团队合作精神；
4.对代谢和代谢相关疾病有强烈兴趣、有细胞生物学或神经生物学研究背景者同等条件下优先考虑。
五、福利待遇
1.根据应聘者的工作经验和能力，提供具有市场竞争力的薪酬（详情面谈）；
2.享受五险一金、带薪年假、体检和补充医疗保险等；
3.支持个人发展，提供必要的工作相关专业培训；
4.为有科研热情且有一定科研能力的应聘者提供充足的深造机会。
六、申请方法
应聘者请将以下材料按照如下顺序打包发送至igm@cimrbj.ac.cn，请【点击下方“立即投递/投递简历”，即刻进行职位报名】，各项材料以“姓名+资料名称”命名，邮件主题请注明“应聘者名字+具体应聘职位”。
1.个人简历、研究兴趣或计划；
2.学术成果或奖励清单（如有）；
3.2名推荐人的姓名及联系方式（仅限博士后应聘）；
4.其他能证明科研能力的相关电子文件。
联系人：任老师
联系地址：北京市丰台区右安门外西头条10号-首都医学科学创新中心
本招聘长期有效，至招聘到合适人选为止。
ABOUT CIMR
Chinese Institutes for Medical Research (CIMR) is a newly founded institution dedicated to fundamental and translational medical research. The CIMR is located at the main campus of theCapitalMedicalUniversity,Beijing,Chinaand committed to building a scientist-centered governance framework and fostering a diverse and inclusive work environment. For more information, please visit our website: www.cimrbj.ac.cn
ABOUT IGM
The Institute for Genetics and Molecular Medicine (IGM) is dedicated to advancing research on congenital genetic diseases, cancer, metabolic disorders, and immune-related diseases. We focus on integrating genetic research with the development of diagnostic and therapeutic technologies, aiming to translate disease research into clinical applications. Leveraging the abundant clinical resources of affiliated hospitals ofCapitalMedicalUniversity, IGM supports translational research that bridges bench to bedside. We encourage close collaboration between laboratories and clinical departments to identify disease-causing genes from clinical samples, conduct mechanistic studies and therapeutic development in the lab, and rapidly validate and optimize diagnostic and treatment approaches in patient populations.
Laboratory Introduction
Liming Wang is Investigator and Director of Institute for Genetics and Molecular Medicine, Chinese Institutes for Medical Research,Beijing, and doctoral supervisor.
The laboratory has long focused on researching the neurobiological regulatory mechanisms of body metabolism. It has published numerous research papers in renowned journals such as Nature, Nature Neuroscience, PNAS, eLife, and Cell Research. Meanwhile, it is committed to public science communication and education, publishing popular science books including The Biology Cultivation of Foodies, God's Scalpel, What Is Life, Laughing to the End, and Virus Science for the Busy, with a circulation of over 300,000 copies. The laboratory has successively won awards such as the Wenjin Book Award from the National Library of China, the National Excellent Popular Science Works Award from the Ministry of Science and Technology, and the Wu Dayou Popular Science Writing Award.
Lab website:QR→（请点击链接查看详情）
Laboratory Research Directions
The survival and health of animals, including humans, largely depend on the precise regulation and maintenance of energy and essential nutrient levels in the body, and the central nervous system (CNS) plays an indispensable role in this regard. By real-time sensing of energy and nutrient reserves within the body, as well as the distribution of food in the environment, the CNS ensures metabolic balance in animals through sophisticated behavioral regulation. Once this regulatory mechanism is disrupted, it may trigger a series of neural and metabolic diseases, including eating disorders and obesity.
Our laboratory has broad interests in biological questions related to the interaction between the nervous system and metabolic system. Our recent research will primarily use techniques such as quantitative behavioral analysis, in vivo calcium imaging, genetic screening and analysis, single-cell transcriptomics, and circuit tracing in Drosophila and mouse models to investigate the following two independent but interrelated biological questions:
How does the nervous system participate in the regulation of energy and essential nutrient metabolism in the body?
How do various organs in animals collaborate in the regulation of body metabolism and the occurrence of metabolic diseases?
Open Positions
Research Assistant
Main Responsibilities
a. Assist in or independently conduct research projects.
b. Participate in laboratory management and provide administrative support.
Qualifications
a. Master’s degree or higher in cell biology, neurobiology, or related fields; bachelor’s degree holders with relevant experimental experience will also be considered on a priority basis.
b. Strong resilience, passion for research, and commitment to a scientific career.
c. High ethical standards, excellent hands-on skills, diligence, and teamwork abilities.
d. Priority given to candidates with CET-6 certificate or equivalent proof of English proficiency, or those planning to pursue graduate studies.
Research Directions
a. Engage in cell-related experiments, including cell culture management, plasmid transfection, stable cell line construction, cell staining, imaging, KO library screening, and metabolite screening.
b. Perform neurocircuitry-related experiments, such as stereotaxic brain injections, fiber photometry, optogenetics/chemogenetics, two-photon in vivo imaging, and tissue clearing imaging.
c. Engage in Drosophila neurocircuitry research, including behavioral assays, in vivo/ex vivo calcium imaging, fluorescent brain slice imaging, optogenetics, and fly stock management.
Postdoctoral Researcher
Main Responsibilities
a. Conduct independent research under the guidance of the principal investigator (PI) and co-mentors, while collaborating with team members.
b. Assist in laboratory management and public affairs.
Qualifications
a. Ph.D. degree (or expected to graduate within 6 months), generally within three years of graduation, in biology, basic medicine, or related fields.
b. First-author publication in a peer-reviewed journal (or accepted for publication).
c. Ability to conduct independent research, strong passion for science, rigorous attitude, and teamwork spirit.
d. Priority given to candidates with a strong interest in metabolism/metabolic diseases (e.g., neuro-metabolism or metabolic disorders in cancer) or backgrounds in cell biology/neurobiology.
Welfare Treatment
a. Competitive salary based on the applicant’s work experience and ability (salary negotiable).
b. Social insurance and housing fund, supplementary medical insurance, physical examination and paid annual leave.
c. Opportunities for career development and available professional guidance.
d. Ample opportunities for further academic promotion for outstanding candidates.
How to apply
Interested applicants should compile the following materials in order and send them to igm@cimrbj.ac.cn, naming each file as Name + Document Title and using the email subject line Applicant Name + Position Applied For:
a. CV and a detailed statement of research interests and future plans.
b. List of academic achievements/awards .
c. Names and contact details of two referees (for postdoctoral applicants only).
d. Additional supporting materials (e.g., representative research papers, project reports) to demonstrate research capabilities.
Contact Person: Ms. Ren
Email: igm@cimrbj.ac.cn
Address: No.10 Xitoutiao, Youanmenwai, Fengtai District,Beijing
This recruitment will remain open until suitable candidates are selected.
Candidates are encouraged to apply as early as possible.
信息来源于网络，如有变更请以原发布者为准。
微信客服赵老师 ：15201695861
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